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In a recent edition of the New England Journal of Medicine there were two original articles and an editorial discussing a large placebo controlled, randomised study of 25,871 people in the United States using what is known as a 2 X 2 factorial design which involved Fish oil, Vitamin D and placebo. There were four possible combinations i.e. Fish oil/placebo; Fish oil/Vitamin D; Vitamin D/placebo;...

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